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Trehalose CAS 99-20-7

Trehalose is a naturally occurring non-reducing disaccharide, composed of two glucose molecules. It is widely found in plants, fungi, bacteria, and invertebrates. Renowned for its exceptional ability to stabilize proteins and protect cellular structures against damage from drying, freezing, and heat, trehalose is a highly valued ingredient in the food, pharmaceutical, and cosmetic industries. Its mild sweetness, about 45% that of sucrose, and clean taste profile make it an excellent sugar alternative. Trehalose is also known for its high glass transition temperature and low hygroscopicity.
Availability:
  • 99-20-7

  • bosschem

  • 99-20-7

Product name: Trehalose
Englishalias:D-(+)-TREHALOSE;D-TREHALOSE;(2R,2'R,3S,3'S,4S,4'S,5R,5'R,6R,6'R)-6,6'-oxybis(2-(hydroxyMethyl)tetrahydro-2H-pyran-3,4,5-triol);TREHALOSE(P);ALPHA-D-TREHALOSE;ALPHA,ALPHA-D-TREHALOSE;MYCOSE;TREHALOSE

CAS: 99-20-7
Molecular formula: C₁₂H₂₂O₁₁
Appearance: White crystalline powder
Package: 25kg/bag

What is Trehalose?

Trehalose is a naturally occurring non-reducing disaccharide, composed of two glucose molecules. It is widely found in plants, fungi, bacteria, and invertebrates. Renowned for its exceptional ability to stabilize proteins and protect cellular structures against damage from drying, freezing, and heat, trehalose is a highly valued ingredient in the food, pharmaceutical, and cosmetic industries. Its mild sweetness, about 45% that of sucrose, and clean taste profile make it an excellent sugar alternative. Trehalose is also known for its high glass transition temperature and low hygroscopicity.

COA:

Test Item(检测项目)

Unit(单位)

Result(结果)

Assay (on dry basis)(干基含量)

%

≥ 98.0

Loss on Drying(干燥失重)

%

≤ 1.5

Residue on Ignition(炽灼残渣)

%

≤ 0.05

pH (5% aqueous solution)(5% 水溶液 pH 值)

-

5.0 - 6.7

Specific Rotation(比旋度)

[α]²⁰D

+197° to +201°

Heavy Metals (as Pb)(重金属,以铅计)

mg/kg

≤ 5

Arsenic (As)(砷)

mg/kg

≤ 1

Application:

1.Food Industry: Trehalose used as a sweetener, texture modifier, and shelf-life extender in beverages, confectionery, baked goods, and seafood. It effectively prevents starch retrogradation, protein denaturation, and fat oxidation.

2.Pharmaceuticals: Trehalose serves as a protective excipient in lyophilized (freeze-dried) injectables, vaccines, and diagnostic kits to protect bioactive ingredients from stress during drying and storage.

3.Cosmetics & Personal Care: Trehalose acts as a highly effective moisturizer and humectant in skincare products like creams, lotions, and serums. It protects skin cells from dehydration and environmental stress.

4.Biotechnology: Trehalose used as a stabilizer for enzymes, antibodies, and other labile biomolecules during research, development, and storage.

5.Agriculture: Trehalose applied in seed coatings and biopesticides to enhance resistance to drought and heat stress.

Safety profile:

Trehalose is generally recognized as safe (GRAS) by the FDA and other international regulatory bodies. It is non-toxic, non-irritating, and well-tolerated by the human body. It is a naturally occurring sugar and is considered vegan.

Storage requirements:

Store in a cool, dry, and well-ventilated area.
Keep the container tightly closed to protect from moisture.
Avoid contact with strong oxidizing agents.

Transport & Packaging:

Trehalose is typically supplied in 25 kg multi-layer paper bags with polyethylene inner liner.
Also available in 500 kg or 1000 kg palletized bags upon request.
Classified as non-hazardous for transport.


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Chemical detection methods

  • Spectroscopic Analysis Methods

    Ultraviolet-Vis Spectrophotometry (UV-Vis)
    Infrared Spectroscopy (IR/FTIR)
    Atomic Absorption Spectroscopy (AAS)
    X-ray Fluorescence Spectroscopy (XRF)
    Nuclear Magnetic Resonance Spectroscopy (NMR)

  • Chromatographic Analysis

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    High Performance Liquid Chromatography (HPLC)
    Ion Chromatography (IC)
    Thin Layer Chromatography (TLC)

  • Mass Spectrometry Analysis

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    ICP-MS: Trace Metal Elements (ppb Level)
    TOF-MS: Precise Molecular Weight Determination

  • Electrochemical analysis methods
    Polypotentiometric methods
    Conductivity methods
    Polarographic methods / Voltammetric methods
    Coulometric analysis
  • Thermal Analysis Methods
    Thermogravimetric Analysis (TGA)
    Differential Scanning Calorimetry (DSC)
    Differential Thermal Analysis (DTA)
  • Classical wet chemical analysis
    Titration analysis
    Gravity analysis
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