N-Fluorobenzenesulfonimide Cas 133745-75-2

NFSI is a novel, stable, and mild fluorinating reagent that can introduce fluorine atoms adjacent to carbonyl groups in organic molecules. It can perform monofluorination reactions on electron rich aromatic compounds, enol silyl ethers, enol lithium salts, etc. The current research hotspots include the Nazarov cyclization reaction catalyzed by iron or cobalt to form a five membered ring, and the asymmetric catalysis of enantioselective alpha fluorination.