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Praziquantel 55268-74-1

1-a]-isoquinolin-4-one,2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino-[2;2-cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydro-4h-pyrazino(2,1-a)isoquinolin-4;4h-pyrazino(2,1-a)isoquinolin-4-one,2-(cyclohexylcarbonyl)-1,2,3,6,7,Chemicalbook11b-hexah;4H-pyrazino-[2,1-a]-isoquinolin-4-one,2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-;biltricide;droncit;Praziquantelforsystemsuitability;2-(Cyclohexanecarbonyl)-1,3,4,6,7,11b-hexahydro-4H-pyrazino[2,1-α]isoquinolin-4-one
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  • 55268-74-1

  • bosschemical

  • 55268-74-1


Praziquantel Basic information
Product Name: Praziquantel
CAS: 55268-74-1
MF: C19H24N2O2
MW: 312.41
EINECS: 259-559-6
Mol File: 55268-74-1.mol
Praziquantel Chemical Properties
Melting point 136-138 C
Boiling point 1377℃
density 1.1209 (rough estimate)
refractive index 1.5600 (estimate)
Fp >110°(230°F)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility ethanol: soluble5mg/mL
pka -0.98±0.20(Predicted)
form powder or crystals
color Crystals from EtOAc/hexane
Water Solubility Freely soluble in ethanol or dichloromethane. Slightly soluble in water
Merck 137,802
BRN 761557
BCS Class 2
EPA Substance Registry System Praziquantel (55268-74-1)

COA:


Items tested

Specifications  (USP40)

Results

Description

We or practically white crystalline powder

Conform


Identification

IR: The infrared spectrum of a potassium bromide dispersion is

Consistent with a reference standard

HPLC: The retention time of the major peak of the sample solution

corresponds to that ofthe standard solution,as obtained m assay

Confoan


Conform

Loss on drying

0.5%

0.1%

0.25%



0.06%

Residue on ignition



Phosphate

<005%

<0.05%


Related compounds


Assay by HPLC

(On dry basis)



Residue Solvents



Particle size

Impurity A ::S;0.2%

0.02%


Impurity B 0.2%

0.11%


Impurity C 0.2%

0.02%


98.5% ~ 101.0%

99.2%


Dichloromethane:  600ppm

ND


Ethyl acetate: 5000ppm

174ppm


Ethanol:  500叩pm

538ppm


D(0.9):   lOOµm

Conform

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