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Laurocapram 59227-89-3

Lauryl azetone is a novel skin permeation enhancer first reported by the American scientist Stoughton in the early 1980s. Its chemical name is 1-n-dodecylazepin-2-one, commonly abbreviated as azetone. At room temperature, azetone is a colorless, odorless, non-toxic, and non-irritating, oily, transparent liquid. It is lubricious, easy to apply, and highly penetrating. As a widely used organic chemical, it has garnered increasing attention due to its highly effective transdermal properties and non-toxic safety profile. It promotes the transdermal penetration of both hydrophilic and hydrophobic compounds.
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  • 59227-89-3

Laurocapram Basic information

Chemical properties Penetration enhancer Application References

Product Name:

Laurocapram

CAS:

59227-89-3

MF:

C18H35NO

MW:

281.48

EINECS:

261-668-9

Mol File:

59227-89-3.mol

Laurocapram Chemical Properties

Melting point

-7°

Boiling point

bp50m 160°

density

0.906-0.926

refractive index

1.470-1.473

storage temp.

Sealed in dry,Room Temperature

solubility

Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)

pka

-0.43±0.20(Predicted)

form

Oil

color

Colourless

Merck

145,385

Cosmetics Ingredients Functions

SKIN CONDITIONING

InChI

InChI=1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-13-16-19-17-14-11-12-15-18(19)20/h2-17H2,1H3

InChIKey

AXTGDCSMTYGJND-UHFFFAOYSA-N

SMILES

N1(CCCCCCCCCCCC)CCCCCC1=O

LogP

6.570 (est)

CAS DataBase Reference

59227-89-3(CAS DataBase Reference)

EPA Substance Registry System

Laurocapram (59227-89-3)

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Chemical detection methods

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  • Classical wet chemical analysis
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    Gravity analysis
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