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Isotretinoin CAS 4759-48-2

TretinoinImpurity1(TretinoinEPImpurityA);AntiAcnePowerfulIsotretinoinPowderIsotretinoinPharmaceuticalRawMaterials;IsotretinoinCapsules;Isotretinoin-D5/13-cChemicalbookis-Retinoicacid-D5;Roaccutan;(2Z,4E,6E,8E)-3,7-diMethyl-9-(2,6,6-triMethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoicacid;ISOTRETINON;AdifferentdiMensionacid
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  • 4759-48-2

  • bosschem

  • 4759-48-2

Isotretinoin Basic information
Product Name: Isotretinoin
Synonyms: Tretinoin Impurity 1(Tretinoin EP Impurity A);Anti Acne Powerful Isotretinoin Powder Isotretinoin Pharmaceutical Raw Materials;Isotretinoin Capsules;Isotretinoin-D5/13-cis-Retinoic acid-D5;Roaccutan;(2Z,4E,6E,8E)-3,7-diMethyl-9-(2,6,6-triMethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid;ISOTRETINON;A different diMension acid
CAS: 4759-48-2
MF: C20H28O2
MW: 300.44
EINECS: 225-296-0
Product Categories: Other APIs;intermediates;Organic acids;APIs;API;BUSPAR;Antibiotics;Intermediates & Fine Chemicals;Pharmaceuticals;Retinoids;4759-48-2
Mol File: 4759-48-2.mol
Isotretinoin Chemical Properties
Melting point 172-175 °C (lit.)
Boiling point 381.66°C (rough estimate)
density 1.0597 (rough estimate)
refractive index 1.4800 (estimate)
storage temp. -20°C
solubility Practically insoluble in water, soluble in methylene chloride, slightly soluble in ethanol (96 per cent). It is sensitive to air, heat and light, especially in solution. Carry out all operations as rapidly as possible and avoid exposure to actinic light; use freshly prepared solutions.
pka 4.76±0.33(Predicted)
form Fine Crystalline Powder
color Yellow-orange to orange
Water Solubility insoluble
λmax 354nm(EtOH)(lit.)
Merck 145,228
Stability: Stable, but probably air and light sensitive. Combustible. Incompatible with strong oxidizing agents.
InChIKey SHGAZHPCJJPHSC-YCNIQYBTSA-N
CAS DataBase Reference 4759-48-2(CAS DataBase Reference)
EPA Substance Registry System Isotretinoin (4759-48-2)

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