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Hydrocortisone acetate CAS 50-03-3


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  • 50-03-3

  • bosschem

  • 50-03-3

Hydrocortisone acetate Basic information
Product Name: Hydrocortisone acetate
Synonyms: (11beta)-21-(Acetoxy)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione;11,17-Dihydroxy-3,20-dioxopregn-4-en-21-yl acetate;11-beta,17-alpha-dihydroxy-21-acetoxypregesterone;11beta17alpha-Dihydroxy-21-acetoxypregesterone;17-alpha-hydrocorticosterone21-acetate;17alpha-Hydrocorticosterone-21-acetate;Cortisone Acetate EP Impurity A(Hydrocortisone Acetate);Hydrocortisone Impurity 3(Hydrocortisone EP Impurity C)
CAS: 18325
MF: C23H32O6
MW: 404.5
EINECS: 200-004-4
Product Categories: Adrenal cortical hormone drugs;API;Biochemistry;Hydroxyketosteroids;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Veterinaries;Steroid and Hormone;Hormone Drugs;50-03-3
Mol File: 50-03-3.mol
Hydrocortisone acetate Chemical Properties
Melting point 223 °C (dec.)(lit.)
Boiling point 446.1°C (rough estimate)
alpha D25 +166° (c = 0.4 in dioxane); D25 +150.7° (c = 0.5 in acetone)
density d420 1.289
refractive index 1.4593 (estimate)
Fp 223°C
storage temp. 0-6°C
solubility Practically insoluble in water, slightly soluble in anhydrous ethanol and in methylene chloride
pka 12.42±0.70(Predicted)
form Solid
color White to Off-White
Water Solubility Insoluble in water.
Decomposition 223 ºC
Merck 144,787
BRN 2066841
Stability: Stable, but may be light or moisture sensitive. Incompatible with strong oxidizing agents.
LogP 2.19
CAS DataBase Reference 50-03-3(CAS DataBase Reference)
NIST Chemistry Reference Hydrocortisone acetate(50-03-3)




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