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Dithioerythritol CAS 6892-68-8 DTE

Dithioerythritol, also known as dithioerythritol (DTE), is a stereoisomer of dithiothreitol (DTT). The two hydroxyl groups of DTT are in the Su configuration, while the two hydroxyl groups of DTE are in the Red configuration. Application of dithioerythritol, also known as dithioerythritol (DTE), can be used as a reducing agent and deprotection agent for thiolated DNA. It is also commonly used for the reduction of disulfide bonds in proteins to prevent the formation of intramolecular or intermolecular disulfide bonds between cysteine residues in proteins.
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Dithioerythritol Basic information
Product Name: Dithioerythritol
CAS: 6892-68-8
MF: C4H10O2S2
MW: 154.25
EINECS: 229-998-8
Mol File: 6892-68-8.mol
Dithioerythritol Chemical Properties
Melting point  82-84 °C(lit.)
Boiling point  247.65°C (rough estimate)
density  1.156 (estimate)
refractive index  1.5200 (estimate)
storage temp.  2-8°C
solubility  H2O: 10 mg/mL, clear, colorless
form  Powder
pka pK1:9.5 (25°C)
color  White to pale yellow or beige
PH 4.0-6.0 (25℃, 0.1M in H2O)
Water Solubility  Soluble
λmax λ: 260 nm Amax: 0.400
λ: 280 nm Amax: 0.050
Sensitive  Air Sensitive
BRN  1719756
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey VHJLVAABSRFDPM-ZXZARUISSA-N
CAS DataBase Reference 6892-68-8(CAS DataBase Reference)
EPA Substance Registry System 1,4-Dithioerythritol (6892-68-8)
Absorption ≤0.4 at 280 in H2O at 0.1M
≤0.6 at 260 in H2O at 0.1M

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