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26016-99-9
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26016-99-9
| Disodium phosphonomycin Basic information | |
| Product Name: | Disodium phosphonomycin |
| Synonyms: | [(2R,3S)-3-Methyloxiran-2-yl]phosphonic acid disodium salt;Fosfomycin sodium;disodium [(2R,3S)-3-methyloxiran-2-yl]-bis(oxidanidyl)-oxo-$l^{5}-phosphane;disodium [(2R,3S)-3-methyloxiran-2-yl]-dioxido-oxo-$l^{5}-phosphane;disodium keto-[(2R,3S)-3-methyloxiran-2-yl]-dioxido-phosphorane;Sodium ((2S,3R)-3-methyloxiran-2-yl)phosphonate;2S)-1;(1,2-epoxypropyl)-,disodiumsalt(1r,2s)(-)-phosphonicaci |
| CAS: | 26016-99-9 |
| MF: | C3H8NaO4P |
| MW: | 162.06 |
| EINECS: | 247-409-2 |
| Product Categories: | Peptide Synthesis/Antibiotics;Antibiotic Explorer;chiral;Intermediates & Fine Chemicals;Pharmaceuticals;Antibiotics;API;antibiotic |
| Mol File: | 26016-99-9.mol |
| Disodium phosphonomycin Chemical Properties | |
| Melting point | >300°C |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | H2O: 50 mg/mL, clear, colorless |
| form | neat |
| color | White to Off-White |
| Water Solubility | Freely soluble in water or aqueous solution |
| BRN | 4604425 |
| Stability: | Hygroscopic |
| InChIKey | QZIQJIKUVJMTDG-OTUWWBTESA-L |
| CAS DataBase Reference | 26016-99-9(CAS DataBase Reference) |
TEST | SPECIFICATIONS | REFERENCE |
Characters | White oralmost white,very hygroscopic powder Slightly soluble in water,methanol,practically insoluble in ethanol and in methy chloride | White oralmost white,very hygroscopic powder |
Identification - By IR - Reaction of calcium |
- The infrared absorption spectrum of sample in the same with Fosfomycin Calcium CRS - It gives reaction (11) of cnlcium | Meets Positive |
PH | Between 8.1 9.6 | 8.4 |
Specific Optical Rotation | Between -11.0°and -13.0° (anhydrous sudstance) | -12.2° |
Impurity A[Calcium(1,2-dihydroxypr opyl)phosphonate] | Not more than 1.55% | 0.33% |
Heavy Metals | Not more than 20ppm | ≤20ppm |
water | Not more than 1.0% | 0.56% |
Bacterial Endotoxins | Not more than 0.083IU/mg | ≤0.083IU/mg |
Assay(On dride basis) | Not more than 95.0% and not more than 101.0% | 98.60% |
Conclusion: Comply with EP 9.0 | ||
| Disodium phosphonomycin Basic information | |
| Product Name: | Disodium phosphonomycin |
| Synonyms: | [(2R,3S)-3-Methyloxiran-2-yl]phosphonic acid disodium salt;Fosfomycin sodium;disodium [(2R,3S)-3-methyloxiran-2-yl]-bis(oxidanidyl)-oxo-$l^{5}-phosphane;disodium [(2R,3S)-3-methyloxiran-2-yl]-dioxido-oxo-$l^{5}-phosphane;disodium keto-[(2R,3S)-3-methyloxiran-2-yl]-dioxido-phosphorane;Sodium ((2S,3R)-3-methyloxiran-2-yl)phosphonate;2S)-1;(1,2-epoxypropyl)-,disodiumsalt(1r,2s)(-)-phosphonicaci |
| CAS: | 26016-99-9 |
| MF: | C3H8NaO4P |
| MW: | 162.06 |
| EINECS: | 247-409-2 |
| Product Categories: | Peptide Synthesis/Antibiotics;Antibiotic Explorer;chiral;Intermediates & Fine Chemicals;Pharmaceuticals;Antibiotics;API;antibiotic |
| Mol File: | 26016-99-9.mol |
| Disodium phosphonomycin Chemical Properties | |
| Melting point | >300°C |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | H2O: 50 mg/mL, clear, colorless |
| form | neat |
| color | White to Off-White |
| Water Solubility | Freely soluble in water or aqueous solution |
| BRN | 4604425 |
| Stability: | Hygroscopic |
| InChIKey | QZIQJIKUVJMTDG-OTUWWBTESA-L |
| CAS DataBase Reference | 26016-99-9(CAS DataBase Reference) |
TEST | SPECIFICATIONS | REFERENCE |
Characters | White oralmost white,very hygroscopic powder Slightly soluble in water,methanol,practically insoluble in ethanol and in methy chloride | White oralmost white,very hygroscopic powder |
Identification - By IR - Reaction of calcium |
- The infrared absorption spectrum of sample in the same with Fosfomycin Calcium CRS - It gives reaction (11) of cnlcium | Meets Positive |
PH | Between 8.1 9.6 | 8.4 |
Specific Optical Rotation | Between -11.0°and -13.0° (anhydrous sudstance) | -12.2° |
Impurity A[Calcium(1,2-dihydroxypr opyl)phosphonate] | Not more than 1.55% | 0.33% |
Heavy Metals | Not more than 20ppm | ≤20ppm |
water | Not more than 1.0% | 0.56% |
Bacterial Endotoxins | Not more than 0.083IU/mg | ≤0.083IU/mg |
Assay(On dride basis) | Not more than 95.0% and not more than 101.0% | 98.60% |
Conclusion: Comply with EP 9.0 | ||
