Product name: Cremophor EL
English alias: Polyoxyl 35 Castor Oil; PEG-35 Castor Oil; Ethoxylated Castor Oil
CAS: 61791-12-6
Molecular formula: C₆₀H₁₁₄O₂₉ (approximate, as it is a mixture)
Appearance: Viscous, yellowish to amber oily liquid
Package: 25kg/drum,200kg/drum,1ton/drum
What is Cremophor EL？
Cremophor EL is a non-ionic surfactant and solubilizer derived from the ethoxylation of castor oil with approximately 35 moles of ethylene oxide. It is widely used in pharmaceutical formulations, cosmetics, and industrial applications. Cremophor EL acts as a solubilizer for poorly soluble drugs and active ingredients, enhancing bioavailability and formulation stability. In cosmetics, it functions as an emulsifier, dispersing agent, and consistency enhancer. It is a clear to yellowish, viscous oily liquid that is soluble in water and many organic solvents.
COA
Product name: Cremophor EL | Specification: 40 | Test date: 22.05.27 |
Test item | Standard | Result |
Appearance | Light yellow paste | Light yellow paste |
PH | 5.0-7.0 | 5.65 |
Cloud point（℃） | 70-84 | 76.2 |
Water（%） | ≤1.0 | 0.23 |
Application
Applied in creams, lotions, and personal care products to stabilize emulsions and improve consistency
Functions as a carrier for lipophilic active ingredients in cosmetic and dermatological preparations
Used in veterinary formulations to enhance drug solubility and delivery
Effective as a dispersing agent for pigments and essential oils in water-based systems
Used in biochemical applications for solubilizing membrane proteins and lipids
Solubilizer/Emulsifier:
Cremophor EL is used in formulations to help mix oily or nonpolar substances with water.
Formulation ingredient:
It is used in various products, including cosmetics and pharmaceuticals
Safety profile
Cremophor EL is generally regarded as safe and non-toxic when used in appropriate concentrations. However, in some injectable drug formulations, it has been associated with hypersensitivity reactions, so usage must comply with regulatory guidelines. For cosmetic and topical use, it is well tolerated and non-irritating to most skin types. Avoid direct ingestion or inhalation of concentrated product.
Storage requirements
Store in a tightly sealed container in a cool, dry place
Keep away from heat, direct sunlight, and moisture
Avoid freezing; product may solidify at low temperatures and should be gently warmed before use
Transport & Packaging
Cremophor EL is available in standard 25 kg plastic drums or customized packaging upon request. It is classified as non-hazardous and can be transported according to general chemical transportation standards.
