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170729-80-3
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170729-80-3
Aprepitant Basic information | |
Anti-Vomiting drug during chemotherapy Dose and usage Side effects Uses | |
Product Name: | Aprepitant |
Synonyms: | CS-274;Aprepitant (MK-0869, L-754030);5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one;Emend;MK-0869;5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,;5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one, Emend;Aprepitant(MK-0869) |
CAS: | 170729-80-3 |
MF: | C23H21F7N4O3 |
MW: | 534.43 |
EINECS: | 677-636-6 |
Mol File: | 170729-80-3.mol |
Aprepitant Chemical Properties | |
Melting point | 244-246°C |
alpha | D25 +69° (c = 1.00 in methanol) |
density | 1.51±0.1 g/cm3(Predicted) |
storage temp. | Sealed in dry,2-8°C |
solubility | Soluble in DMSO (>25 mg/ml) |
pka | 8.06±0.20(Predicted) |
form | powder |
color | white to beige |
optical activity | [α]/D +61 to +71°, c = 1.0 in methanol |
Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
CAS DataBase Reference | 170729-80-3(CAS DataBase Reference) |
Aprepitant Basic information | |
Anti-Vomiting drug during chemotherapy Dose and usage Side effects Uses | |
Product Name: | Aprepitant |
Synonyms: | CS-274;Aprepitant (MK-0869, L-754030);5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one;Emend;MK-0869;5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,;5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one, Emend;Aprepitant(MK-0869) |
CAS: | 170729-80-3 |
MF: | C23H21F7N4O3 |
MW: | 534.43 |
EINECS: | 677-636-6 |
Mol File: | 170729-80-3.mol |
Aprepitant Chemical Properties | |
Melting point | 244-246°C |
alpha | D25 +69° (c = 1.00 in methanol) |
density | 1.51±0.1 g/cm3(Predicted) |
storage temp. | Sealed in dry,2-8°C |
solubility | Soluble in DMSO (>25 mg/ml) |
pka | 8.06±0.20(Predicted) |
form | powder |
color | white to beige |
optical activity | [α]/D +61 to +71°, c = 1.0 in methanol |
Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
CAS DataBase Reference | 170729-80-3(CAS DataBase Reference) |