99% Triclosan Cas 3380-34-5

1. Product Overview

Triclosan is a chlorinated aromatic ether with broad-spectrum antibacterial and antifungal activity — one of the most studied antimicrobial agents of the past half-century. It acts by inhibiting a bacterial fatty-acid-synthesis enzyme (ENR), giving effective control of Gram-positive, Gram-negative bacteria and fungi at low concentrations.

For decades triclosan served consumer soaps, hand washes, toothpaste, deodorants and household products. Its regulatory landscape has since been reshaped:the EU and China have removed it from permitted cosmetic preservatives — while the US EPA still registers it for non-consumer antimicrobial uses in textiles, plastics and industrial products, and it remains allowed in FDA-regulated toothpaste in the United States. This page therefore presents the product's chemistry, legitimate current uses and its full regulatory status.

Core value propositions:

Broad-Spectrum Antimicrobial Action:

● effective control of bacteria and fungi via ENR enzyme inhibition at low concentrations;

Textile & Material Antimicrobial Treatment:

● an EPA-registered antimicrobial for textile finishes, plastics and non-consumer articles;

Industrial Preservation:

● a preservative and antimicrobial additive for coatings, industrial fluids and specialty materials;

2. Product Information (Quick Facts)

3. Chemistry & Mechanism

Triclosan (2,4,4′-trichloro-2′-hydroxydiphenyl ether) is a bisphenol-type chlorinated ether. Its antimicrobial action targets the enoyl-acyl carrier protein reductase (ENR/FabI), an enzyme essential to bacterial fatty-acid synthesis: triclosan binds the enzyme’s active site and blocks it, halting membrane-lipid production and cell growth,triclosan is selectively toxic to microbes at low concentrations.

The compound is thermally stable (boiling point > 280 °C), soluble in organic solvents and alkaline water (pKa ≈ 7.9), and technically straightforward to compound into polymers, textiles and coatings. Environmental and endocrine-related concerns — including persistence, transformation products and hormonal activity reported in studies — underlie its restricted regulatory status. Buyers must match the product to currently permitted uses in their destination market.

4. Key Features & Benefits

● Broad-spectrum antimicrobial: effective against Gram-positive, Gram-negative bacteria and fungi at low concentration.

● ENR-targeted mechanism: blocks bacterial fatty-acid synthesis with selective microbial toxicity.

● High thermal stability: stable above 280 °C — compatible with polymer and textile processing.

● EPA-registered non-consumer uses: legitimate antimicrobial use in textiles, plastics and industrial products.

● Industrial preservation value: effective antimicrobial additive for coatings, fluids and materials.

● Well-characterized chemistry: decades of toxicological and environmental data available for risk evaluation.

● Regulatory clarity: exact current status in the US, EU and China documented for compliance.

5. Main Applications

5.1 Broad-Spectrum Antimicrobial Action (Core Mechanism)

Triclosan’s antimicrobial chemistry underpins all its uses:

● Bacteriostatic and fungistatic control of surfaces and materials at low loading;

● Compatibility with polymer, textile and coating matrices for durable antimicrobial effects;

● Historical consumer use (soaps, toothpaste, deodorants) — now restricted as described in the regulatory section.

5.2 Textile & Material Antimicrobial Treatment (EPA-Registered Uses)

● Textile finishes: antimicrobial treatment of fabrics and nonwovens;

● Plastics and articles: antimicrobial additive for cutting boards, kitchenware and specialty goods;

● Non-consumer products: EPA-registered applications outside rinse-off antiseptic washes;

● Material protection: prevents odor, staining and microbial degradation of products.

5.3 Industrial Preservation

● Coatings and paints: in-can preservation and film protection;

● Industrial fluids: antimicrobial control in process and metalworking fluids;

● Specialty materials: preservation of adhesives, inks and sealants;

● Technical grade supply for formulation and research.

6. Packaging, Storage

Packaging (customizable):

● 20 kg / 25 kg fiber drum with PE liner, 25 kg multi-wall bag, or 500 kg – 1,000 kg FIBC;

Storage:

● Keep in a cool, dry, well-ventilated area away from direct sunlight and heat;

● Keep containers tightly closed to prevent contamination and moisture pick-up;

● Store away from strong oxidizers and incompatible materials;

● Recommended storage temperature 5 °C – 35 °C.

7. Why Choose Jinan Future Chemical Co., Ltd.?

● Factory-direct supply: own production capacity, transparent pricing, no middleman markup;

● Stable quality: strict internal control, every batch tested, COA with every shipment;small trial orders accepted.

● Compliance-first service: we advise on the currently permitted applications in your destination market;

● Export experience: familiar with sea/air shipping documentation for chemical commodities, complete paperwork support;

8. FAQ

Q1: What is triclosan used for today?

Triclosan is an antimicrobial active. Its currently permitted uses are mainly non-consumer: textile and material antimicrobial treatment, plastics additives and industrial preservation (US EPA-registered). It remains allowed in FDA-regulated toothpaste in the United States,and as a cosmetic preservative in the EU and China.

Q3: Is triclosan safe to handle?

Triclosan has low acute toxicity in normal industrial handling, but long-term studies have associated it with endocrine-disrupting activity, thyroid effects and environmental persistence, so it must be used only within currently permitted applications. Use gloves, goggles and dust protection, avoid release to the environment, and comply strictly with the destination market's regulations. It is an industrial chemical, not a food ingredient.