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Piroctone olamine CAS:68890-66-4 OCTO

Piroctone Olamine is an ethanolamine salt derived from hydroxamic acid compounds, known for its powerful antifungal and antibacterial properties. It is widely used as an active ingredient in anti-dandruff shampoos, scalp care products, and personal care formulations. Piroctone Olamine effectively inhibits the growth of Malassezia species, which are linked to dandruff and other scalp conditions. Unlike some conventional agents like zinc pyrithione, Piroctone Olamine is considered milder and less irritating to the skin and eyes. It is a white to off-white crystalline powder that is soluble in ethanol and slightly soluble in water.
Availability:
  • 68890-66-4

  • bosschem

  • 68890-66-4

Product name: Piroctone Olamine
English alias: Piroctone ethanolamine salt; Octopirox; PEO
CAS: 68890-66-4

Molecular formula: C16H30N2O3
Appearance: White or off-white crystalline powder
Package: 25kg/drum

What is Piroctone Olamine?

Piroctone Olamine is an ethanolamine salt derived from hydroxamic acid compounds, known for its powerful antifungal and antibacterial properties. It is widely used as an active ingredient in anti-dandruff shampoos, scalp care products, and personal care formulations. Piroctone Olamine effectively inhibits the growth of Malassezia species, which are linked to dandruff and other scalp conditions. Unlike some conventional agents like zinc pyrithione, Piroctone Olamine is considered milder and less irritating to the skin and eyes. It is a white to off-white crystalline powder that is soluble in ethanol and slightly soluble in water.

COA

Item

Specification

Result

Appearance

White or off-white powder

Conforms

Assay

≥97%

97.82%

pH (1% aqueous)

6.0 – 8.0

6.48

Melting Point

≥260℃

267.8℃

Drying Loss

≤0.5%

0.22%

Conclusion


PASS

Application

Used as an active ingredient in anti-dandruff shampoos and scalp treatments
Inhibits the growth of fungi such as Malassezia that cause dandruff and seborrheic dermatitis
Applied in hair care products to improve scalp condition and reduce flaking
Used in deodorants and other personal care products for its antimicrobial properties
Compatible with various surfactants and cosmetic formulations without reducing foam or stability
Mild on the skin and suitable for long-term daily use products

Safety profile

Piroctone Olamine is considered a safe and effective ingredient when used within recommended concentrations. It has low toxicity, is non-sensitizing, and is generally well-tolerated by skin and eyes. Patch testing is advised for sensitive skin. It is also more environmentally friendly than heavy-metal-based antifungal agents and has a favorable safety profile in rinse-off and leave-on products.

Storage requirements

Store in a tightly sealed container in a cool, dry place
Avoid direct sunlight and high humidity
Keep away from incompatible substances such as strong acids and oxidizing agents

Transport & Packaging

Piroctone Olamine is supplied in fiber drums with a standard net weight of 25 kg or customized packaging based on customer requirements. It should be transported in accordance with regulations for non-hazardous chemical substances.


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Chemical detection methods

  • Spectroscopic Analysis Methods

    Ultraviolet-Vis Spectrophotometry (UV-Vis)
    Infrared Spectroscopy (IR/FTIR)
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    Nuclear Magnetic Resonance Spectroscopy (NMR)

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  • Mass Spectrometry Analysis

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    TOF-MS: Precise Molecular Weight Determination

  • Electrochemical analysis methods
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    Conductivity methods
    Polarographic methods / Voltammetric methods
    Coulometric analysis
  • Thermal Analysis Methods
    Thermogravimetric Analysis (TGA)
    Differential Scanning Calorimetry (DSC)
    Differential Thermal Analysis (DTA)
  • Classical wet chemical analysis
    Titration analysis
    Gravity analysis
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