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N-acetylglucosamine (CAS 7512-17-6) is a naturally occurring functional monosaccharide . It is an important precursor for the synthesis of hyaluronic acid and chondroitin in the body, and is therefore commonly used in the field of dietary supplements to maintain joint health and moisturize the skin.
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7512-17-6
bosschemical
7512-17-6
N-Acetyl-D-Glucosamine Basic information | |
Product Name: | N-Acetyl-D-Glucosamine |
CAS: | 7512-17-6 |
MF: | C8H15NO6 |
MW: | 221.21 |
EINECS: | 231-368-2 |
Mol File: | 7512-17-6.mol |
N-Acetyl-D-Glucosamine Chemical Properties | |
Melting point | 211 °C (dec.) (lit.) |
alpha | 42 º (c=2,water,2 hrs) |
vapor pressure | 8Pa at 20℃ |
refractive index | +39.0 to +42.0 ° (C=1, H2O) |
storage temp. | -20°C |
solubility | Soluble in concentrated hydrochloric acid, sulfuric acid, phosphoric acid and formic acid. Insoluble in water, dilute acids, dilute alkalis, concentrated alkalis and organic solvents. |
Boiling point | 636.4±55.0 °C(Predicted) |
density | 1.54 g/cm3 |
pKa | 13.04±0.20(Predicted) |
form | saline suspension |
color | white to off-white |
biological source | crab (red) |
Optical Rotation | Alpha type +75 → +41 Beta type -22 → +41.3 |
Water Solubility | H2O: 50 mg/mL colorless to faint yellow solution, clear to very slightly hazy |
Sensitive | Hygroscopic |
Merck | 144,458 |
BRN | 1727589 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
Cosmetic Ingredient Review (CIR) | N-Acetyl-D-Glucosamine (7512-17-6) |
InChI | 1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8/m1/s1 |
InChIKey | OVRNDRQMDRJTHS-ROGOILFBSA-N |
SMILES | CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O |
LogP | -2.2 at 23.7℃ |
CAS DataBase Reference | 7512-17-6(CAS DataBase Reference) |
EPA Substance Registry System | N-Acetylglucosamine (7512-17-6) |
ITEM | SPECIFICATION | TESTMETHOD | RESULTS |
Properties (physical): | |||
Appearance | White Crystalline, Free Flowing Powder | USP38. - <695> | Complies |
Bulk Density | NLT0.40g/ml | USP38.- <616> | [0.41g/ml |
As Tapped Density | Meets the requirements of USP38 | USP38. - <616> | Complies |
Particle Size | NLT 90% through 100 Mesh | USP38.- <811> | Complies |
Analytical Properties: | |||
Assay (HPLC) | 98.0~102.0% (on the dried basis) | USP38. -.<621> | 98.85% |
Absorb | <0.25a.u. (10.0% Water Solut.-280nm) | USP38. -.<851> | 10.05a.u. |
Specific Rotation(a）p2o | +39.0°~+43.0° | USP38. - <781S> | 40.15 |
PH (20mg/ml.aq.sol.） | 6.0~8.0 | USP38.- <791> | 7.78 |
Loss on Drying | NMTO.5% | USP38-- <731> | 10.06% |
Residue on Ignition | NMT 0.1% | USP38.- <281> | 10.03% |
Chloride (Cl) | NMTO.1% | USP38- <541> | 0.01% |
Melting Range | 196°C~205°C | USP38. -- <741> | 202.3°C~203.4°C |
Heavy Metals | NMT 10 ppm | USP38. - <231> II | Complies |
Iron (fe) | NMT 10 ppm | USP38.-.<241> | Complies |
Lead | NMT 0.5 ppm | USP38. - <251> | [0.05ppm |
Cadmium | NMT 0.5 ppm | GB/T 5009.15——2003 | Complies |
Arsenic (As) | NMT 1.0 ppm | USP3. - <211> II | Complies |
Mercury | NMT 0.1 ppm | USP38.- <261> | 00.06ppm |
Organic volatile impurities | Meets the Requirements | USP38. - <467> I | Complies |
Microbial: | |||
Total Aerobic | NMT 1,000 cfu/g | USP38 - <61> | NMT 100 cfu/g |
Yeast & Mold | NMT 100 cfu/g | USP38 - <61> | NMT 30 cfu/g |
E.Coli | Negative in 1g | USP38 - <61> | Negative |
Salmonella | Negative in 1g | USP38.- <61> | Negative |
Staphylococcus Aureus | Negative in 10g | USP38. - <61> | Negative |
Enterobacteria & other gram neg | NMT 100 cfu/g | USP38 - <61> | NMT 30 cfulg |
