N-Acetyl-D-Glucosamine CAS 7512-17-6

N-Acetyl-D-Glucosamine Basic information

Product Name:

N-Acetyl-D-Glucosamine

CAS:

7512-17-6

MF:

C8H15NO6

MW:

221.21

EINECS:

231-368-2

Mol File:

7512-17-6.mol

N-Acetyl-D-Glucosamine Chemical Properties

Melting point

211 °C (dec.) (lit.)

alpha

42 º (c=2,water,2 hrs)

vapor pressure

8Pa at 20℃

refractive index

+39.0 to +42.0 ° (C=1, H2O)

storage temp.

-20°C

solubility

Soluble in concentrated hydrochloric acid, sulfuric acid, phosphoric acid and formic acid. Insoluble in water, dilute acids, dilute alkalis, concentrated alkalis and organic solvents.

Boiling point

636.4±55.0 °C(Predicted)

density

1.54 g/cm3

pKa

13.04±0.20(Predicted)

form

saline suspension

color

white to off-white

biological source

crab (red)

Optical Rotation

Alpha type +75 → +41 Beta type -22 → +41.3

Water Solubility

H2O: 50 mg/mL colorless to faint yellow solution, clear to very slightly hazy

Sensitive

Hygroscopic

Merck

144,458

BRN

1727589

Stability:

Stable. Incompatible with strong oxidizing agents.

Cosmetic Ingredient Review (CIR)

N-Acetyl-D-Glucosamine (7512-17-6)

InChI

1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8/m1/s1

InChIKey

OVRNDRQMDRJTHS-ROGOILFBSA-N

SMILES

CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O

LogP

-2.2 at 23.7℃

CAS DataBase Reference

7512-17-6(CAS DataBase Reference)

EPA Substance Registry System

N-Acetylglucosamine (7512-17-6)

ITEM

SPECIFICATION

TESTMETHOD

RESULTS

Properties (physical):

Appearance

White Crystalline, Free Flowing Powder

USP38. - <695>

Complies

Bulk Density

NLT0.40g/ml

USP38.- <616>

[0.41g/ml

As Tapped Density

Meets the requirements of USP38

USP38. - <616>

Complies

Particle Size

NLT 90% through 100 Mesh

USP38.- <811>

Complies

Analytical Properties:

Assay (HPLC)

98.0~102.0% (on the dried basis)

USP38. -.<621>

98.85%

Absorb

<0.25a.u. (10.0% Water Solut.-280nm)

USP38. -.<851>

10.05a.u.

Specific Rotation(a）p2o

+39.0°~+43.0°

USP38. - <781S>

40.15

PH (20mg/ml.aq.sol.）

6.0~8.0

USP38.- <791>

7.78

Loss on Drying

NMTO.5%

USP38-- <731>

10.06%

Residue on Ignition

NMT 0.1%

USP38.- <281>

10.03%

Chloride (Cl)

NMTO.1%

USP38- <541>

0.01%

Melting Range

196°C~205°C

USP38. -- <741>

202.3°C~203.4°C

Heavy Metals

NMT 10 ppm

USP38. - <231> II

Complies

Iron (fe)

NMT 10 ppm

USP38.-.<241>

Complies

Lead

NMT 0.5 ppm

USP38. - <251>

[0.05ppm

Cadmium

NMT 0.5 ppm

GB/T 5009.15——2003

Complies

Arsenic (As)

NMT 1.0 ppm

USP3. - <211> II

Complies

Mercury

NMT 0.1 ppm

USP38.- <261>

00.06ppm

Organic volatile impurities

Meets the Requirements

USP38. - <467> I

Complies

Microbial:

Total Aerobic

NMT 1,000 cfu/g

USP38 - <61>

NMT 100 cfu/g

Yeast & Mold

NMT 100 cfu/g

USP38 - <61>

NMT 30 cfu/g

E.Coli

Negative in 1g

USP38 - <61>

Negative

Salmonella

Negative in 1g

USP38.- <61>

Negative

Staphylococcus Aureus

Negative in 10g

USP38. - <61>

Negative

Enterobacteria & other gram neg

NMT 100 cfu/g

USP38 - <61>

NMT 30 cfulg