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Madecassic acid CAS 18449-41-7

Madecassoside, a core active ingredient extracted from traditional plant centella asiatica, belongs to the triterpenoid saponin class of organic compounds and is currently a widely studied natural product in skincare research
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  • 18449-41-7

Madecassic acid Basic information

Product Name:

Madecassic acid

CAS:

18449-41-7

MF:

C30H48O6

MW:

504.71

EINECS:

240-851-7

Mol File:

18449-41-7.mol

Madecassic acid Chemical Properties

Melting point

270°C (dec.)

Boiling point

641.7±55.0 °C(Predicted)

density

1.23±0.1 g/cm3(Predicted)

storage temp.

2-8°C

solubility

DMSO (Sparingly), Methanol (Slightly, Heated)

form

Solid

pka

4.63±0.70(Predicted)

color

White to Pale Red

Major Application

food and beverages

Cosmetics Ingredients Functions

SKIN CONDITIONING

InChIKey

PRAUVHZJPXOEIF-MRQYELSVNA-N

SMILES

O[C@H]1[C@@H]2[C@@]([C@@H]3[C@]([C@@]4(CC[C@@]5([C@@H]([C@H]([C@@H](CC5)C)C)C4=CC3)C(=O)O)C)(C1)C)(C[C@H]([C@@H]([C@]2(CO)C)O)O)C

LogP

4.321 (est)

固体.jpg
通用.jpg

Test item

Standards

Assay results

Color

White powder

Conforms

TLC

Conforms

Conforms

Assays(HPLC)

Madecassoside+AsiaticosideB>95.0%

Madecassoside+AsiaticosideB: 96.08%

Loss on drying

$3.0%

Madecassoside: 85.49%

Ash

<1.0%

Asiaticoside B: 10.59%

Heavy metals

<20PPM

1.83%

Pb

<O.5PPM

0.47%

Hg

<0.05PPM

Conforms

Cd

<0.3PPM

Conforms

Cu

<5PPM

Conforms

As

<O.5PPM

Conforms

BHC

<0.2PPM

Conforms

DDT

<0.2PPM

Conforms

Aldrin

<0.1PPM

Conforms

Total bacteria count

Less than 1000CFU/G

Conforms

Yeast/moulds

Less than 100CFU/G

Conforms

Salmonella

Negative

<10CFU/G

E-Coli

Negative

<10CFU/G

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Chemical detection methods

  • Spectroscopic Analysis Methods

    Ultraviolet-Vis Spectrophotometry (UV-Vis)
    Infrared Spectroscopy (IR/FTIR)
    Atomic Absorption Spectroscopy (AAS)
    X-ray Fluorescence Spectroscopy (XRF)
    Nuclear Magnetic Resonance Spectroscopy (NMR)

  • Chromatographic Analysis

    Gas Chromatography (GC)
    High Performance Liquid Chromatography (HPLC)
    Ion Chromatography (IC)
    Thin Layer Chromatography (TLC)

  • Mass Spectrometry Analysis

    GC-MS / LC-MS/MS: Qualitative and Quantitative Analysis
    ICP-MS: Trace Metal Elements (ppb Level)
    TOF-MS: Precise Molecular Weight Determination

  • Electrochemical analysis methods
    Polypotentiometric methods
    Conductivity methods
    Polarographic methods / Voltammetric methods
    Coulometric analysis
  • Thermal Analysis Methods
    Thermogravimetric Analysis (TGA)
    Differential Scanning Calorimetry (DSC)
    Differential Thermal Analysis (DTA)
  • Classical wet chemical analysis
    Titration analysis
    Gravity analysis
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