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Guanidine thiocyanate CAS 593-84-0

Guanidine thiocyanate is a white crystalline substance with a melting point of 116-121 ℃. At 20 ℃, the pH value of 6mol/L in water is 4.5-6, and its solubility is complete dissolution. It is a type of uncoupling agent, a strong protein denaturing agent that can dissolve proteins and cause the disappearance of protein secondary structures, cellular structure degradation, and rapid separation of nuclear proteins from nucleic acids. Used for transgender lysis of cells; Extract RNA and DNA without RNAse and DNAse activity.

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Model:
593-84-0
Brand:
bosschemical
Code:
593-84-0

Product Description

Guanidine thiocyanate

CAS 593-84-0

Alias：GTC;GUANIDINE THIOCYANATE;GUANIDINE HYDROTHIOCYANATE;GUANIDINE ISOTHIOCYANATE;GUANIDINE MONOTHIOCYANATE;GUANIDINE RHODANIDE;GUANIDINIUM THIOCYANATE;GUANIDINIUM ISOTHIOCYANATE

Molecular formula：CH5N3.CHNS

Molecular weight：118.16

Structural formula：

硫氰酸胍结构式

1.Performance and use

Guanidine thiocyanate is mainly used in biomedicine, chemical reagents, etc

Guanidine thiocyanate is used as a chaotropic agent and strong denaturing agent for denaturing and lysing cells; Extract RNA and DNA.

2.Technical indicators

SPECIFICATION PROPERTIES	STANDARD	RESULTS
Appearance	White crystalline powder	Conforms
Assay,%	≥99.0	99.18
MP, ℃	115.0-120.0	116.9-119.0
Solubility(6mol/L aq.)	Clear, colorless solution	Conforms
Heavy Metals,ppm	≤5	Conforms
Water Content,%	≤0.5	0.11
PH(1M aq.)	4.5-7.0	6.19
Ultraviolet absorbance(6mol/L aq.)	≤0.10	0.043
Ultraviolet absorbance(6mol/L aq.)	≤0.05	0.003

3. Packaging and storage

Packaging specification: 190kg/drum，which can also be determined according to user needs

During transportation, it is necessary to protect against sunlight, rain, and high temperatures.

The product should be stored in a cool, dark, ventilated place, away from sources of fire.

4. Safety protection

Pay attention to labor protection when handling it and avoid contact with skin, eyes, etc.

After contact, rinse immediately with plenty of water

Guanidine thiocyanate CAS 593-84-0

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Chemical detection methods

Spectroscopic Analysis Methods

Ultraviolet-Vis Spectrophotometry (UV-Vis)
Infrared Spectroscopy (IR/FTIR)
Atomic Absorption Spectroscopy (AAS)
X-ray Fluorescence Spectroscopy (XRF)
Nuclear Magnetic Resonance Spectroscopy (NMR)

Chromatographic Analysis

Gas Chromatography (GC)
High Performance Liquid Chromatography (HPLC)
Ion Chromatography (IC)
Thin Layer Chromatography (TLC)

Mass Spectrometry Analysis

GC-MS / LC-MS/MS: Qualitative and Quantitative Analysis
ICP-MS: Trace Metal Elements (ppb Level)
TOF-MS: Precise Molecular Weight Determination

Electrochemical analysis methods

Polypotentiometric methods
Conductivity methods
Polarographic methods / Voltammetric methods
Coulometric analysis

Thermal Analysis Methods

Thermogravimetric Analysis (TGA)
Differential Scanning Calorimetry (DSC)
Differential Thermal Analysis (DTA)

Classical wet chemical analysis

Titration analysis
Gravity analysis