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7704-73-6
bosschemical
7704-73-6
Product Name: Sodium Fumarate
English alias: Sodium fumarate; Disodium fumarate； Fumaric acid disodium salt； Sodium (E)-butenedioate
CAS number: 7704-73-6
Molecular formula: C ₄ H ₂ Na ₂ O ₄
Appearance: White to off white crystalline powder at room temperature, dissolved in water to form a transparent liquid without precipitation or layering
Conventional packaging: 25kg/bag; 50kg/barrel; 1kg/bottle
Sodium fumarate is an organic carboxylate salt generated by the neutralization reaction of fumaric acid (trans butenedioic acid) and sodium hydroxide. It belongs to unsaturated binary carboxylate compounds, and its core feature is the retention of the trans double bond (C=C) of fumaric acid and two carboxylate sodium salt groups (- COONa) in the molecular structure, which combines chemical stability and biocompatibility. Its double bond structure endows it with certain reactivity and can participate in polymerization reactions; The sodium carboxylate group gives it excellent water solubility and ion exchange ability, and can be converted into fumaric acid in vivo, participating in the tricarboxylic acid cycle and having good bioavailability.
COA:
Tests | Specification |
Result |
Appearance |
White or almostwhite, fine powder with agglomerates of flat, circular particles. |
Almost white powder |
Solubility | Practicallyinsoluble in water, slightlysoluble in methanol, practicallyinsolublein acetone and in anhydrous ethanol. |
Consistentwiththe regulations |
Identification | Infrared absorption spectrophotometry. Comparison:sodium stearyl fumarate CRS. |
Consistent with the regulations |
Related substances | any impurity: maximum 0.5 per cent |
0.2% |
total: maximum 5.0 per cent |
0.38% | |
Water | maximum 5.0 per cent |
3.1% |
Assay | 99.0 per cent to 101.5 per cent(anhydroussubstance) |
100.3% |
Sodium fumarate is a non-toxic substance .It is non irritating upon skin contact and inhalation of dust may cause mild respiratory dryness (such as dry throat) in sensitive populations. Food grade and pharmaceutical grade products can be directly used in food contact and human medicinal scenarios, while cosmetic grade products have good skin compatibility; It is recommended to wear N95 dust masks (to avoid inhaling dust) and nitrile protective gloves (to prevent powder adhesion) during operation, and no special protective equipment is required; If accidentally entering the eyes, rinse with plenty of water, there is no risk of irritation; The product should be avoided from being ingested by children, and a "non food" label (non food grade product) should be posted in the storage area.
keep the product dry
relative humidity <60%
protect product against influences of weather and contamination
During transportation, it is necessary to load and unload gently. When using forklifts or pallets for handling, avoid collisions and squeezing of packaging (especially cardboard drums and glass bottles) to prevent dust leakage caused by packaging damage; Wear anti slip gloves and dust masks during manual handling. It is strictly prohibited to throw or roll the packaging to avoid product adhesion and dust inhalation; When handling pharmaceutical and food grade products, avoid contact with oil stains to prevent contamination.
Product Name: Sodium Fumarate
English alias: Sodium fumarate; Disodium fumarate； Fumaric acid disodium salt； Sodium (E)-butenedioate
CAS number: 7704-73-6
Molecular formula: C ₄ H ₂ Na ₂ O ₄
Appearance: White to off white crystalline powder at room temperature, dissolved in water to form a transparent liquid without precipitation or layering
Conventional packaging: 25kg/bag; 50kg/barrel; 1kg/bottle
Sodium fumarate is an organic carboxylate salt generated by the neutralization reaction of fumaric acid (trans butenedioic acid) and sodium hydroxide. It belongs to unsaturated binary carboxylate compounds, and its core feature is the retention of the trans double bond (C=C) of fumaric acid and two carboxylate sodium salt groups (- COONa) in the molecular structure, which combines chemical stability and biocompatibility. Its double bond structure endows it with certain reactivity and can participate in polymerization reactions; The sodium carboxylate group gives it excellent water solubility and ion exchange ability, and can be converted into fumaric acid in vivo, participating in the tricarboxylic acid cycle and having good bioavailability.
COA:
Tests | Specification |
Result |
Appearance |
White or almostwhite, fine powder with agglomerates of flat, circular particles. |
Almost white powder |
Solubility | Practicallyinsoluble in water, slightlysoluble in methanol, practicallyinsolublein acetone and in anhydrous ethanol. |
Consistentwiththe regulations |
Identification | Infrared absorption spectrophotometry. Comparison:sodium stearyl fumarate CRS. |
Consistent with the regulations |
Related substances | any impurity: maximum 0.5 per cent |
0.2% |
total: maximum 5.0 per cent |
0.38% | |
Water | maximum 5.0 per cent |
3.1% |
Assay | 99.0 per cent to 101.5 per cent(anhydroussubstance) |
100.3% |
Sodium fumarate is a non-toxic substance .It is non irritating upon skin contact and inhalation of dust may cause mild respiratory dryness (such as dry throat) in sensitive populations. Food grade and pharmaceutical grade products can be directly used in food contact and human medicinal scenarios, while cosmetic grade products have good skin compatibility; It is recommended to wear N95 dust masks (to avoid inhaling dust) and nitrile protective gloves (to prevent powder adhesion) during operation, and no special protective equipment is required; If accidentally entering the eyes, rinse with plenty of water, there is no risk of irritation; The product should be avoided from being ingested by children, and a "non food" label (non food grade product) should be posted in the storage area.
keep the product dry
relative humidity <60%
protect product against influences of weather and contamination
During transportation, it is necessary to load and unload gently. When using forklifts or pallets for handling, avoid collisions and squeezing of packaging (especially cardboard drums and glass bottles) to prevent dust leakage caused by packaging damage; Wear anti slip gloves and dust masks during manual handling. It is strictly prohibited to throw or roll the packaging to avoid product adhesion and dust inhalation; When handling pharmaceutical and food grade products, avoid contact with oil stains to prevent contamination.
