Betadex Sulfobutyl Ether Sodium CAS 182410-00-0 SBE-Beta-CD-Na

Product name: Betadex Sulfobutyl Ether Sodium
English alias: SBE-β-CD; Sulfobutylether β-Cyclodextrin Sodium Salt
CAS: 182410-00-0
Molecular formula: C70H119Na7O56S7

Appearance: White to off-white powder
Package: 1kg/bag, 5kg/bag, 25kg/drum

Introduction:

What is Sulfobutyl-Beta-Cyclodextrin Sodium？

Betadex Sulfobutyl Ether Sodium is a chemically modified cyclodextrin derivative that is widely used as a solubility enhancer and stabilizer in pharmaceutical formulations. It is an anionic, highly water-soluble compound that can form inclusion complexes with poorly soluble drugs, thereby improving their bioavailability and stability. SBE-β-CD is particularly valuable in injectable and oral drug delivery systems due to its low toxicity and high biocompatibility. It is also used in cosmetics, food, and analytical chemistry. The product typically appears as a white to off-white free-flowing powder.

COA:

项目（Item）	标准要求（Standard Requirement）	检测结果（Test Result）
Infrared Spectroscopy Identification	Spectrum consistent with standard reference	Spectrum consistent with standard reference
Liquid Chromatography Identification	Main peak retention time of sample solution consistent with standard reference	Main peak retention time of sample solution consistent with standard reference
Degree of Substitution	Meets the requirement for average degree of substitution	Meets the requirement
Heavy Metals	≤ 5 ppm	< 5 ppm
Beta-Cyclodextrin	≤ 0.1%	Not detected

Application:

1.Improves solubility and stability:

It increases the solubility of poorly soluble drugs by forming non-covalent inclusion complexes, and its hydrophilic surface provides excellent water solubility and stability for the drug

2.Enhances safety and efficacy:

It helps reduce drug toxicity, minimizes hemolysis, and controls drug release, leading to improved patient outcomes

3.Cosmetics:

Acts as a stabilizer and solubilizer in cosmetic products to improve active ingredient efficacy.

4.Analytical Chemistry:

Used in chromatographic methods and sample preparation to improve analyte solubility.

5.Food Industry:

Employed as a flavor encapsulant and stabilizer in food products.

Safety profile:

Sulfobutyl-Beta-Cyclodextrin Sodium is generally recognized as safe (GRAS) for use in pharmaceutical and cosmetic applications. It exhibits low toxicity and is well-tolerated in humans. However, as with any excipient, appropriate safety assessments should be conducted for specific applications. It is non-irritating and non-sensitizing under normal use conditions.

Storage requirements:

Store in a cool, dry, and well-ventilated place

Keep container tightly closed

Protect from moisture and light

Relative humidity < 60%

Transport & Packaging:

Sulfobutyl-Beta-Cyclodextrin Sodium is available in sealed aluminum bags or fiber drums. Standard packaging includes 1 kg/bag, 5 kg/bag, and 25 kg/drum. Customized packaging is available upon request. The product is stable under normal transport conditions and is not classified as hazardous.