Tetrahydrolinalool Cas 78-69-3 THL

Product Name: 1,1,3,3-Tetramethylguanidine
English Alias: TMG; Tetramethylguanidine
CAS Number: 80-70-6
Molecular Formula: C₅H₁₃N₃
Molecular Weight: 115.18 g/mol
Appearance: Colorless to light yellow clear liquid
Package: 1 kg/bottle, 5 kg/bottle (HDPE plastic bottle)

What is 1,1,3,3-Tetramethylguanidine？

1,1,3,3-Tetramethylguanidine (TMG) is a strong organic base appearing as a colorless to light yellow clear liquid with a characteristic amine odor. It is soluble in water and most organic solvents. The compound exhibits high basicity (pKa = 13.6) and low nucleophilicity, making it an excellent catalyst and base in organic synthesis. It is hygroscopic and should be stored under dry conditions.

COA (Certificate of Analysis):

Analytical Item	Analytical Standard	Analytical Result
Appearance	Colorless liquid	Qualified
Purity	≥99.0%	99.72%
Moisture	≤0.20%	0.088%

Application:

Strong organic base:

TMG is often used as a substitute for more expensive non-nucleophilic bases like DBU and DBN.

Polyurethane production:

It acts as a base-catalyst in the production of polyurethanes.

Chemical synthesis:

TMG is used in a variety of synthetic processes, such as promoting the oxidation of alcohols to aldehydes and ketones.

Alkylation:

It is employed in alkylation reactions, for example, to prepare alkyl nitriles from alkyl halides.

Safety Profile:

1,1,3,3-Tetramethylguanidine is corrosive and causes severe skin burns and eye damage. May cause respiratory irritation. Use appropriate personal protective equipment including chemical-resistant gloves, face shield, and adequate ventilation when handling. Avoid contact with skin and eyes. The substance is toxic to aquatic life. For comprehensive safety information, always consult the full Safety Data Sheet (SDS).

Storage Requirements:

Store in a cool, dry, well-ventilated area away from direct sunlight. Keep containers tightly closed and sealed under inert atmosphere. Maintain storage temperature between 15-25°C. Keep away from acids and strong oxidizing agents. Handle under dry conditions.

Transport & Packaging:

1,1,3,3-Tetramethylguanidine is packaged in HDPE plastic bottles (1 kg or 5 kg net weight per bottle), placed in sturdy outer containers. Transport as corrosive material according to applicable regulations. Ensure containers are properly sealed and protected from physical damage during transportation. Store away from incompatible materials.