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130-95-0
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130-95-0
Quinine Basic information | |
Pharmacology and mechanism of action Indications Side effects Contraindications and precautions Interactions Preparations description Uses pharmacokinetics Side effects Drug interactions Precautions overdose References: | |
Product Name: | Quinine |
Synonyms: | (R)-(6-Methoxyquinolin-4-yl)((1R,2R,4R,5S)-5-vinylquinuclidin-2-yl)Methanol;(1R)-(6-Methoxyquinolin-4-yl)(5-vinylquinuclidin-2-yl)Methanol;(-)-QUININE FOR RESOLUTION OF RACEMATES;(R)-[(2S,4S,5R)-1-Aza-5-vinylbicyclo[2.2.2]oct-2-yl](6-methoxyquinolin-4-yl)methanol;Quinine, (R)-[(2S,4S,5R)-1-Aza-5-ethenylbicyclo[2.2.2]oct-2-yl](6-methoxyquinolin-4-yl)methanol;Quinine Anhydrous, for Fluorescene;(8R,9S)-Quinidine-d3;(9S)-6'-Methoxycinchonan-9-ol-d3 |
CAS: | 130-95-0 |
MF: | C20H24N2O2 |
MW: | 324.42 |
EINECS: | 205-003-2 |
Mol File: | 130-95-0.mol |
Quinine Chemical Properties | |
Melting point | 173-175 °C(lit.) |
alpha | -172 º (c=1, EtOH) |
Boiling point | 462.75°C (rough estimate) |
density | 1.1294 (rough estimate) |
vapor pressure | 0Pa at 25℃ |
refractive index | 1.6250 (estimate) |
Fp | >110°C (>230°F) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | H2O: soluble |
form | Crystalline Powder |
pka | 8.52(at 25℃) |
color | White |
PH Range | Blue I uorescence (3.0) to weak violet I uorescence (5.0);Weak violet I uorescence (9.5) to nonI uorescence (10.0) |
PH | 9.0 (0.5g/l, H2O, 20℃) |
optical activity | [α]25/D 165°, c = 2 in ethanol |
Water Solubility | slightly soluble |
Sensitive | Light Sensitive |
Hydrolytic Sensitivity | 2: reacts with aqueous acid |
Merck | 148,061 |
BRN | 91867 |
Major Application | Bird repellents, sunscreen, antimalarial agent, antiviral agent, antitumor agent, drug-coated coronaryagent, antiparasitic agent, treatment of epilepsy, skeletal muscle spasm, drug-coated coronary stent system |
LogP | 3.17 at 25℃ |
CAS DataBase Reference | 130-95-0(CAS DataBase Reference) |
NIST Chemistry Reference | Quinine(130-95-0) |
EPA Substance Registry System | Quinine (130-95-0) |
Quinine Basic information | |
Pharmacology and mechanism of action Indications Side effects Contraindications and precautions Interactions Preparations description Uses pharmacokinetics Side effects Drug interactions Precautions overdose References: | |
Product Name: | Quinine |
Synonyms: | (R)-(6-Methoxyquinolin-4-yl)((1R,2R,4R,5S)-5-vinylquinuclidin-2-yl)Methanol;(1R)-(6-Methoxyquinolin-4-yl)(5-vinylquinuclidin-2-yl)Methanol;(-)-QUININE FOR RESOLUTION OF RACEMATES;(R)-[(2S,4S,5R)-1-Aza-5-vinylbicyclo[2.2.2]oct-2-yl](6-methoxyquinolin-4-yl)methanol;Quinine, (R)-[(2S,4S,5R)-1-Aza-5-ethenylbicyclo[2.2.2]oct-2-yl](6-methoxyquinolin-4-yl)methanol;Quinine Anhydrous, for Fluorescene;(8R,9S)-Quinidine-d3;(9S)-6'-Methoxycinchonan-9-ol-d3 |
CAS: | 130-95-0 |
MF: | C20H24N2O2 |
MW: | 324.42 |
EINECS: | 205-003-2 |
Mol File: | 130-95-0.mol |
Quinine Chemical Properties | |
Melting point | 173-175 °C(lit.) |
alpha | -172 º (c=1, EtOH) |
Boiling point | 462.75°C (rough estimate) |
density | 1.1294 (rough estimate) |
vapor pressure | 0Pa at 25℃ |
refractive index | 1.6250 (estimate) |
Fp | >110°C (>230°F) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | H2O: soluble |
form | Crystalline Powder |
pka | 8.52(at 25℃) |
color | White |
PH Range | Blue I uorescence (3.0) to weak violet I uorescence (5.0);Weak violet I uorescence (9.5) to nonI uorescence (10.0) |
PH | 9.0 (0.5g/l, H2O, 20℃) |
optical activity | [α]25/D 165°, c = 2 in ethanol |
Water Solubility | slightly soluble |
Sensitive | Light Sensitive |
Hydrolytic Sensitivity | 2: reacts with aqueous acid |
Merck | 148,061 |
BRN | 91867 |
Major Application | Bird repellents, sunscreen, antimalarial agent, antiviral agent, antitumor agent, drug-coated coronaryagent, antiparasitic agent, treatment of epilepsy, skeletal muscle spasm, drug-coated coronary stent system |
LogP | 3.17 at 25℃ |
CAS DataBase Reference | 130-95-0(CAS DataBase Reference) |
NIST Chemistry Reference | Quinine(130-95-0) |
EPA Substance Registry System | Quinine (130-95-0) |