|Ibuprofen Basic information|
|description Indications Used in Particular Diseases Increase stroke risk Precautions Drug Interactions Side Effects|
|Synonyms:||(+/-)-2-(4-ISOBUTYLPHENYL)-PROPIONIC ACID;2-(4-ISOBUTYLPHENYL)PROPIONIC ACID;4-ISOBUTYL-ALPHA-METHYLPHENYLACETIC ACID;AKOS NCG1-0060;(+/-)-ALPHA-METHYL-4-(2-METHYLPROPYL)-BENZENEACETIC ACID;ALPHA-METHYL-4-[2-METHYLPROPYL]BENZENEACETIC ACID;ALPHA-METHYL-4-(ISOBUTYL)PHENYLACETIC ACID;[A-METHYL-4-ISOBUTYL]PHENYLACETIC ACID|
|Product Categories:||pharmacetucial intermediate;Pharmaceutical ingredients;APIs;Inhibitors;Intermediates & Fine Chemicals;API’s;Active Pharmaceutical Ingredients;API;Pharmaceuticals;Lipid signaling;Isotopically Labeled Pharmaceutical Reference Standard;ADVIL;Other APIs|
|Ibuprofen Chemical Properties|
|Melting point||77-78 °C|
|Boiling point||157 °C (4 mmHg)|
|density||1.0364 (rough estimate)|
|refractive index||1.5500 (estimate)|
|solubility||Practically insoluble in water, freely soluble in acetone, in methanol and in methylene chloride. It dissolves in dilute solutions of alkali hydroxides and carbonates.|
|pka||pKa 4.45± 0.04(H2O,t = 25±0.5,I=0.15(KCl))(Approximate)|
|color||white to off-white|
|Stability:||Stable. Combustible. Incompatible with strong oxidizing agents.|
|CAS DataBase Reference||15687-27-1(CAS DataBase Reference)|
|NIST Chemistry Reference||Ibuprofen(15687-27-1)|
|EPA Substance Registry System||Benzeneacetic acid, .alpha.-methyl-4-(2-methylpropyl)- (15687-27-1)|
|Hazardous Substances Data||15687-27-1(Hazardous Substances Data)|
|Toxicity||LD50 in male mice, rats (mg/kg): 495, 626 i.p.; 1255, 1050 orally (Orzalesi)|
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