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Hydrocortisone acetate
| Hydrocortisone acetate Basic information | |
| Adrenocorticotropic hormone drugs Indications Contraindications Adverse Reactions Precautions Chemical Property Uses Production methods | |
| Product Name: | Hydrocortisone acetate |
| Synonyms: | (11beta)-21-(Acetoxy)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione;11,17-Dihydroxy-3,20-dioxopregn-4-en-21-yl acetate;11-beta,17-alpha-dihydroxy-21-acetoxypregesterone;11beta17alpha-Dihydroxy-21-acetoxypregesterone;17-alpha-hydrocorticosterone21-acetate;17alpha-Hydrocorticosterone-21-acetate;Cortisone Acetate EP Impurity A（Hydrocortisone Acetate）;Hydrocortisone Impurity 3（Hydrocortisone EP Impurity C） |
| CAS: | 50-03-3 |
| MF: | C23H32O6 |
| MW: | 404.5 |
| EINECS: | 200-004-4 |
| Product Categories: | Adrenal cortical hormone drugs;API;Biochemistry;Hydroxyketosteroids;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Veterinaries;Steroid and Hormone;Hormone Drugs |
| Mol File: | 50-03-3.mol |
| Hydrocortisone acetate Chemical Properties | |
| Melting point | 223 °C (dec.)(lit.) |
| alpha | D25 +166° (c = 0.4 in dioxane); D25 +150.7° (c = 0.5 in acetone) |
| Boiling point | 446.1°C (rough estimate) |
| density | d420 1.289 |
| refractive index | 1.4593 (estimate) |
| Fp | 223°C |
| storage temp. | 0-6°C |
| solubility | Practically insoluble in water, slightly soluble in anhydrous ethanol and in methylene chloride |
| pka | 12.42±0.70(Predicted) |
| Water Solubility | Insoluble in water. |
| Decomposition | 223 ºC |
| Merck | 14,4787 |
| BRN | 2066841 |
| Stability: | Stable, but may be light or moisture sensitive. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 50-03-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Hydrocortisone acetate(50-03-3) |
